From 1956, when the complex ultrastructure of meiotic chromosomes was discovered, 1 until 1985, when the isolation of meiotic chromosome cores was reported, knowledge of the molecular structure of the meiotic chromosome was at best a dream. The dissection of meiotic chromosome structures has become a realistic challenge through the arrival of isolated symptonemal complexes (SCs), monoclonal and polyclonal antibodies against SCs, the possibility for screening expression libraries for genes that encode SC proteins, the isolation of SC‐associated DNA, and the (...) development of techniques for the in situ recognition of DNA sequences in the context of the meiotic chromosome structure. (shrink)

From "Materialism and Revolution" through _Hope Now_, Jean-Paul Sartre was deeply engaged with questions about the meaning and justifiability of violence. In the first comprehensive treatment of Sartre’s views on the subject, Ronald Santoni begins by tracing the full trajectory of Sartre’s evolving thought on violence and shows how the "curious ambiguity" of freedom affirming itself against freedom in his earliest writings about violence developed into his "curiously ambivalent" position through his later writings.

This text provides a comprehensive and timely examination of the most pertinent factors affecting institutional ethics committees, for ethicists, trustees, administrators, physicians, clergy, nurses, social workers, attorneys and others with an interest in ethics committees.

Reid’s previously published writings are substantial, both in quantity and quality. This edition attempts to make these writings more readily available in a single volume. Based upon Hamilton’s definitive two volume 6th edition, this edition is suitable for both students and scholars. Beanblossom and Lehrer have included a wide range of topics addressed by Reid. These topics include Reid’s views on the role of common sense, scepticism, the theory of ideas, perception, memory and identity, as well as his views on (...) moral liberty, duties, and principles. Historical as well as topical considerations guided the selection process. Thus, Reid’s responses to Descartes, Locke, Berkeley, and Hume are included. Through the resulting selections Reid’s influence and impact upon subsequent philosophers is manifested. (shrink)